Biologically Active Substance
hypoxanthine
hy·po·xan·thine [ hahy-puh-zan-theen, -thin ]
Subclass of:
Hypoxanthines
Definitions related to hypoxanthine:
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6-oxopurine, the base in inosine and its derivatives.CRISP ThesaurusNational Institutes of Health, 2006
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A purine and a reaction intermediate in the metabolism of adenosine and in the formation of nucleic acids by the salvage pathway.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A purine-based organic compound in human muscle tissues, Hypoxanthine is formed during purine catabolism as a product of xanthine oxidase action on xanthine, and occasionally is found as a constituent of nucleic acids. The potent anti-inflammatory and cytoprotective effects of purines may be mediated by cell surface adenosine receptors. Hypoxanthine protects against oxidant-induced cell injury by inhibiting activation of nuclear poly(ADP-ribose) polymerase (PARP). (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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