Pharmacologic Substance
ibuprofen Audio
i·bu·pro·fen [ ahy-byoo-proh-fuhn, ahy-byoo-proh-fen ]
Brand Names:
Addaprin; Advil; Caldolor; Counteract IB; Duexis; Genpril; Ibu; Ibudone; Ibuprohm; Ibutab; Ibu-Tab; Motrin; Motrin PM; Neoprofen; Proprinal; Reprexain; Samson 8; Vicoprofen; Wal-Profen; Xylon
Effect:
Decreased Platelet Activating Factor Production; Decreased Prostaglandin Production; Decreased Thromboxane Production
May Prevent:
Pain
May Treat:
Arthritis, Juvenile; Arthritis, Rheumatoid; Bursitis; Dysmenorrhea; Fever; Gout; Inflammation; Menorrhagia; Osteoarthritis; Pain, Postoperative; Premenstrual Syndrome; Spondylitis, Ankylosing
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to ibuprofen:
  • A drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID).
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A nonsteroidal anti-inflammatory agent with analgesic properties used in the treatment of RHEUMATISM and ARTHRITIS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. (NCI05)
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Nonsteroidal analgesic, antipyretic and anti-inflammatory agent that is a propionic acid derivative.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Ibuprofen, nonsteroidal anti-inflammatory drug used in the treatment of minor pain, fever, and inflammation. Like aspirin, ibuprofen works by inhibiting the synthesis of prostaglandins, body chemicals that sensitize nerve endings. The drug may irritate the gastrointestinal tract. Marketed under...
    Encyclopedia Britannica
    Encyclopedia Britannica, Inc., 2020
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.