Pharmacologic Substance
ketoprofen Audio
[ kee-toh-proh-fen ]
Brand Names:
Draxxin KP; Ketofen
Effect:
Decreased Prostaglandin Production
May Treat:
Arthritis, Rheumatoid; Dysmenorrhea; Osteoarthritis
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to ketoprofen:
  • A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of ibuprofen. Ketoprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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