• (ichthyosis) A group of inherited or acquired skin disorders characterized by a dry, thickened, and scaly skin. The skin changes range from mild to severe.
  NCI Thesaurus
  U.S. National Cancer Institute, 2021
• (ichthyosis) An abnormality of the skin characterized the presence of excessive amounts of dry surface scales on the skin resulting from an abnormality of keratinization.
  Human Phenotype Ontology (HPO)
  The Human Phenotype Ontology Project, 2021
• (ichthyosis) Any of several generalized skin disorders characterized by dryness, roughness, and scaliness, due to hypertrophy of the stratum corneum epidermis. Most are genetic, but some are acquired, developing in association with other systemic disease or genetic syndrome.
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2021
• Ichthyosis is scaling and flaking of skin ranging from mild but annoying dryness to severe disfiguring disease. Ichthyosis can also be a sign of systemic disease. Diagnosis is clinical. Treatment involves emollients and sometimes oral retinoids.
  Merck Manuals
  Merck & Co., Inc., 2020
• Ichthyosis refers to a relatively uncommon group of skin disorders characterized by the presence of excessive amounts of dry surface scales. It is regarded as a disorder of keratinization or cornification, and it is due to abnormal epidermal differentiation or metabolism.
  Medscape
  WebMD, 2019
• Ichthyosis is a descriptive term for dry, scaly skin that in some cases may resemble the scales on a fish (ichthys is the Greek root for fish). The inherited ichthyoses are a group of diseases that feature scaling skin as part of their clinical presentation. The underlying defect, mode of inheritance, character, and extent of scaling...
  Epocrates
  Athenahealth, Inc., 2019
• Ichthyosis, a hereditary condition involving dryness and scaliness of the skin brought about by excessive growth of the horny outermost covering of the skin. The dead cells of this horny layer do not slough off at the normal rate but tend instead to adhere to the skin surface to form scales; horny...
  Encyclopedia Britannica
  Encyclopedia Britannica, Inc., 2020