• A common interstitial lung disease of unknown etiology, usually occurring between 50-70 years of age. Clinically, it is characterized by an insidious onset of breathlessness with exertion and a nonproductive cough, leading to progressive DYSPNEA. Pathological features show scant interstitial inflammation, patchy collagen fibrosis, prominent fibroblast proliferation foci, and microscopic honeycomb change.
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2021
• A disease in which the alveoli (tiny air sacs at the end of the bronchioles in the lungs) are overgrown with fibrous tissue. The cause of the disease is unknown and it gets worse over time. Symptoms include difficult, painful breathing and shortness of breath.
  NCI Dictionary of Cancer Terms
  U.S. National Cancer Institute, 2021
• Chronic and progressive fibrosis of the lung parenchyma of unknown cause.
  NCI Thesaurus
  U.S. National Cancer Institute, 2021
• Chronic inflammation and progressive fibrosis of the pulmonary alveolar walls with steady progressive dyspnea; finally, resulting in death from lack of oxygen or right heart failure.
  CRISP Thesaurus
  National Institutes of Health, 2006
• Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial pneumonia, causes progressive pulmonary fibrosis. Symptoms and signs develop over months to years and include exertional dyspnea, cough, and fine (Velcro) crackles. Diagnosis is based on history, physical examination, high-resolution CT, and/or lung...
  Merck Manuals
  Merck & Co., Inc., 2020
• Idiopathic pulmonary fibrosis (IPF) is defined as a specific form of chronic, progressive fibrosing interstitial pneumonia of unknown cause, primarily occurring in older adults, limited to the lungs, and associated with the histopathologic and/or radiologic pattern of usual interstitial pneumonia (UIP). Of the seven listed idiopathic...
  Medscape
  WebMD, 2019
• Idiopathic pulmonary fibrosis (IPF) is a condition in which tissues in the lungs become thick and stiff, or scarred, over time. The lungs then lose their ability to move oxygen to the brain and other parts of the body. Common symptoms include shortness of breath and a dry, hacking cough. In some cases fibrosis happens quickly, while in...
  NIH Genetic and Rare Diseases
  National Center for Advancing Translational Sciences
• A rare, chronic, idiopathic, life-threatening disease that manifests over several years and is characterized by scar tissue within the lungs and progressive dyspnea. It is the most common form of the group of interstitial lung diseases also known as idiopathic interstitial pneumonias, which share clinical features of shortness of breath;...
  Epocrates
  Athenahealth, Inc., 2019