Pharmacologic Substance
iloprost Audio
[ i-loh-prost ]
Brand Names:
Ventavis
Effect:
Pulmonary Arterial Vasodilation; Systemic Arterial Vasodilation
May Treat:
Hypertension, Pulmonary
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to iloprost:
  • A prostacyclin analogue with potential chemopreventive activity. Iloprost binds to the prostacyclin receptor in various target cells, thereby causing vasodilation, inhibition of platelet aggregation, and decreased tumor cell adhesion to endothelium among other effects. Prostacyclin is a naturally occurring eicosanoid with anti-inflammatory, antineoplastic, and anti-metastatic properties. (NCI05)
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A substance that is being studied in the prevention of lung cancer. It belongs to the family of drugs called prostaglandin analogs.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • An eicosanoid, derived from the cyclooxygenase pathway of arachidonic acid metabolism. It is a stable and synthetic analog of EPOPROSTENOL, but with a longer half-life than the parent compound. Its actions are similar to prostacyclin. Iloprost produces vasodilation and inhibits platelet aggregation.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • Specific isomer of hexahydro-5-hydroxy-4- (3-hydroxy-4-methyl-1- octen-6-ynyl) pentalenevaleric acid; prostacyclin analog and agonist; has vasodilator and anticoagulant actions and therefore may be useful for treating a variety of vascular disorders.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.