Pharmacologic Substance
imiquimod Audio
[ ih-mih-kwih-mod ]
Brand Names:
Aldara; Zyclara
Effect:
Increased Cytokine Activity; Increased Cytokine Production
May Treat:
Carcinoma, Basal Cell; Condylomata Acuminata; Keratosis, Actinic
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to imiquimod:
  • A drug used to treat early basal cell skin cancer and certain other skin conditions. It is being studied in the treatment of other types of cancer. Imiquimod is a type of biological response modifier.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A synthetic agent with immune response modifying activity. As an immune response modifier (IRM), imiquimod stimulates cytokine production, especially interferon production, and exhibits antitumor activity, particularly against cutaneous cancers. Imiquimod's proapoptotic activity appears to be related to Bcl-2 overexpression in susceptible tumor cells. (NCI04)
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A topically-applied aminoquinoline immune modulator that induces interferon production. It is used in the treatment of external genital and perianal warts, superficial CARCINOMA, BASAL CELL; and ACTINIC KERATOSIS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.