Immunologic Factor
immunoglobulin M
[ im-yuh-noh-glob-yuh-lin, ih-myoo- em ]
Subclass of:
Immunoglobulin Isotypes
Definitions related to immunoglobulin m:
  • (igm) The major immunoglobulin secreted during a primary immune response. IgM binds with low affinity but high avidity (multiple binding sites) because it not only occurs as monomers but also as pentamers and hexamers.
    NCI
    U.S. National Cancer Institute, 2021
  • A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally was called a macroglobulin.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Pentameric immunoglobulin largely confined to the intravascular pool and the predominant early antibody frequently seen in the immune response to antigenically complex infectious organisms.
    CRISP Thesaurus
    National Institutes of Health, 2006
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