• An infectious process involving the endocardial layer of the heart.
  NCI Thesaurus
  U.S. National Cancer Institute, 2021
• Endocarditis that is caused by an infectious agent.
  NICHD Pediatric Terminology
  U.S. National Cancer Institute, 2021
• Infective endocarditis is infection of the endocardium, usually with bacteria (commonly, streptococci or staphylococci) or fungi. It may cause fever, heart murmurs, petechiae, anemia, embolic phenomena, and endocardial vegetations. Vegetations may result in valvular incompetence or obstruction, myocardial abscess, or mycotic aneurysm....
  Merck Manuals
  Merck & Co., Inc., 2020
• Infective endocarditis (IE) is defined as an infection of the endocardial surface of the heart, which may include one or more heart valves, the mural endocardium, or a septal defect. Its intracardiac effects include severe valvular insufficiency, which may lead to intractable congestive heart failure and myocardial abscesses.
  Medscape
  WebMD, 2019
• Infective endocarditis (IE) is an infection of the inner lining of the heart chambers (endocardium) and valves. This condition is sometimes called "endocarditis," although it is important to distinguish it from non-infective endocarditis. IE is caused by bacteria, fungi, or other germs invading the bloodstream and attaching to the heart....
  NIH Genetic and Rare Diseases
  National Center for Advancing Translational Sciences
• Infective endocarditis (IE) is an infection involving the endocardial surface of the heart, including the valvular structures, the chordae tendineae, sites of septal defects, or the mural endocardium.
  Epocrates
  Athenahealth, Inc., 2019