Hormone
insulin lispro
Brand Names:
Admelog; Humalog; Humalog Mix; Lyumjev
Effect:
Decreased Glycogenolysis; Decreased Lipolysis; Increased Glucose Transport into Cells; Increased Glycogenesis; Increased Lipogenesis; Increased Protein Synthesis
May Treat:
Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Hyperglycemia
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to insulin lispro:
  • A recombinant therapeutic agent which is chemically identical to or similar to endogenous human insulin. In lispro insulin, the amino acid proline at B-28 and the amino acid lysine at B-29 are reversed, resulting in the rapid dissolution of this insulin to a monomer that is absorbed rapidly after subcutaneous administration. Lispro insulin is equipotent to human insulin on a molar basis but its effects are faster and of shorter duration. Endogenous insulin, a pancreatic hormone composed of two polypeptide chains, is important in the normal metabolism of carbohydrates, proteins and fats, promoting glucose utilization and protein synthesis; it has anabolic effects on many types of tissues. (NCI04)
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Insulin that has been modified so that the B-chain contains a LYSINE at position 28 instead of a PROLINE and a PROLINE at position 29 instead of a LYSINE. It is used to manage BLOOD GLUCOSE levels in patients with TYPE 2 DIABETES.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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