Enzyme
integrase
Definitions related to integrase:
  • Integrase is an enzyme that catalyzes the integration of viral DNA into the host genome. These enzymes act to cleave and religate the joints between host DNA and integrated DNA.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Retrovirus encoded protein which covalently links the viral cDNA to host DNA; forms a 'preintegration complex' and catalyzes the viral integration reaction.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Recombinases that insert exogenous DNA into the host genome. Examples include proteins encoded by the POL GENE of RETROVIRIDAE and also by temperate BACTERIOPHAGES, the best known being BACTERIOPHAGE LAMBDA.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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