Immunologic Factor
interferon-alpha
in·ter·fer·on·al·pha
Subclass of:
Interferon Type I
Definitions related to interferon-alpha:
  • (interferon alpha) Major interferon produced by virus-exposed leukocytes; has antiviral activity and activates NK cells; used in the treatment of hairy cell leukemia and other neoplasms.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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