Pharmacologic Substance
ionomycin Audio
[ i-on-oh-my-sin ]
Subclass of:
Fatty Acids, Unsaturated
Definitions related to ionomycin:
  • A divalent calcium ionophore that is widely used as a tool to investigate the role of intracellular calcium in cellular processes.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A polyether antibiotic isolated from Streptomyces conglobatus sp. nov. Trejo with antineoplastic activity. Ionomycin is a calcium ionophore that increases intracellular Ca++ levels, possibly relating to endonuclease activation of lymphocytes and decreased ratio of Bcl-2 to Bax and ultimately apoptosis. In addition, this agent is used to investigate the role of intracellular calcium in cellular processes.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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