Biologically Active Substance
labradimil
Definitions related to labradimil:
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A substance that is being studied for its ability to help other drugs reach the brain. It belongs to the family of drugs called bradykinin agonists.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A synthetic analog of bradykinin. Lobradimil is a potent, specific bradykinin B-2 receptor agonist that stimulates B-2 receptors expressed on the surface of brain capillary endothelial cells, thereby reversibly increasing the permeability of the blood-brain barrier (BBB). Compared to bradykinin, this agent possesses enhanced receptor selectivity, greater plasma stability, and a longer half-life. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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