Pharmacologic Substance
lenalidomide Audio
[ leh-nuh-lih-doh-mide ]
Brand Names:
Revlimid
Effect:
Cellular Growth Phase Reduction; Cellular Proliferation Alteration; Increased Cellular Death; Vascular Growth Decrease
May Treat:
Lymphoma, Mantle-Cell; Multiple Myeloma; Myelodysplastic Syndromes
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to lenalidomide:
  • A drug that is similar to thalidomide, and is used to treat multiple myeloma and certain types of anemia. It is also being studied in the treatment of other types of cancer. Lenalidomide belongs to the family of drugs called angiogenesis inhibitors.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A phthalimide and piperidone derivative that has immunomodulatory and antiangiogenic properties. It is used for the treatment of transfusion-dependent anemia in MYELODYSPLASTIC SYNDROMES, and for the treatment of MULTIPLE MYELOMA, and relapsed or refractory MANTLE CELL LYMPHOMA.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A thalidomide analog with potential antineoplastic activity. Lenalidomide inhibits TNF-alpha production, stimulates T cells, reduces serum levels of the cytokines vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), and inhibits angiogenesis. This agent also promotes G1 cell cycle arrest and apoptosis of malignant cells.
    NCI
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.