Pharmacologic Substance
levamisole Audio
le·va·mi·sole [ lee-va-mih-sole ]
Effect:
Increased Immunologically Active Molecule Activity
May Treat:
Colonic Neoplasms
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to levamisole:
  • An anthelmintic drug. Co-administered with fluorouracil in the treatment of Dukes' stage C colon cancer, levamisole restores immune function through stimulating antibody formation, enhancing T-cell activity, and potentiating macrophage function. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • An antiparasitic drug that is also being studied in cancer therapy with fluorouracil.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • Oral imidazole used as an anthelminthic, effective against roundworms, hookworms and strongyloids; also an immunopotentiator; has been used to stimulate immune response in cancer.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.