Hormone
levothyroxine sodium
Effect:
Cellular Synthetic Activity Alteration; Increased Gluconeogenesis; Increased Metabolic Rate
May Prevent:
Hypothyroidism
May Treat:
Goiter; Myxedema; Thyroid Neoplasms; Thyroiditis, Autoimmune; Thyrotoxicosis
More Information:
ChemID; DailyMed; PDR
Definitions related to levothyroxine sodium:
  • A man-made version of the thyroid hormone thyroxine.
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
  • The sodium salt of levothyroxine, a synthetic levoisomer of thyroxine (T4) that is similar to the endogenous hormone produced by the thyroid gland. In peripheral tissues, levothyroxine is deiodinated by 5'-deiodinase to form triiodothyronine (T3). T3 enters the cell and binds to nuclear thyroid hormone receptors; the activated hormone-receptor complex in turn triggers gene expression and produces proteins required in the regulation of cellular respiration; thermogenesis; cellular growth and differentiation; and the metabolism of proteins, carbohydrates and lipids. T3 also exhibits cardiostimulatory effects.
    NCI
    U.S. National Cancer Institute, 2021
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