Quantitative Concept
linkage disequilibrium
[ ling-kij dis-ee-kwuh-lib-ree-uhm, dis-ee- ]
Subclass of:
genetic linkage
Definitions related to linkage disequilibrium:
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Nonrandom association of linked genes. This is the tendency of the alleles of two separate but already linked loci to be found together more frequently than would be expected by chance alone.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Nonrandom association of linked genes; the occurrence of some genes together, more often than would be expected based upon their physical separation, presumably because the combination confers some selective advantage.NCI ThesaurusU.S. National Cancer Institute, 2021
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When a specific haplotype is almost always associated with a gene mutation; genetic diagnostic method used to decrease uncertainty in linkage analysis.CRISP ThesaurusNational Institutes of Health, 2006
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Where alleles (DNA markers) occur together more often than can be accounted for by chance because of their physical proximity on a chromosome.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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