Disease or Syndrome
localized scleroderma
[ loh-kuh-lahyz d skleer-uh-dur-muh, skler- ]
Subclass of:
Connective Tissue Diseases;
Dermatologic disorders
Definitions related to localized scleroderma:
-
A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. Localized scleroderma typically affects the skin, with formation of patches or lines of thick and unyielding tissue; there can be muscle and underlying tissue involvement as well as occasional joint complications. The affected areas of skin can be restrictive and disfiguring. The shape, depth and location of the affected area is used to classify one of the four types of local scleroderma. An individual can have a combination of localized scleroderma types.NCI ThesaurusU.S. National Cancer Institute, 2021
-
An autoimmune disorder marked by excessive production of collagen resulting in hardening and thickening of skin, with formation of patches or lines of thick and unyielding tissue. There can also be musculoskeletal and underlying tissue involvement. The affected areas of skin can be restrictive and disfiguring.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
-
Localized scleroderma is the skin localized form of scleroderma characterized by fibrosis of the skin causing cutaneous plaques or strips.OrphaNetINSERM, 2021
-
(scleroderma, localized) A term used to describe a variety of localized asymmetrical SKIN thickening that is similar to those of SYSTEMIC SCLERODERMA but without the disease features in the multiple internal organs and BLOOD VESSELS. Lesions may be characterized as patches or plaques (morphea), bands (linear), or nodules.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
-
Localized scleroderma is characterized by thickening of the skin from excessive collagen deposits. Collagen is a protein normally present in our skin that provides structural support. However, when too much collagen is made, the skin becomes stiff and hard. Localized types of scleroderma are those limited to the skin and related tissues...National Center for Advancing Translational Sciences
Return to OpenMD Medical Dictionary
> L
This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.