Pharmacologic Substance
loratadine
Brand Names:
Alavert; Alavert D; Allerclear; Claritin; Claritin-D; Cleartime Indoor & Outdoor Allergies; Dimetapp ND; Loradamed; Tavist Non-Sedating; Wal-itin; Wal-itin D; Wal-vert
Effect:
Decreased Histamine Activity
May Treat:
Rhinitis, Allergic, Perennial;
Urticaria
More Information:
Definitions related to loratadine:
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A piperidine histamine H1-receptor antagonist with anti-allergic properties and without sedative effects. Loratadine blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial smooth muscle, and gastrointestinal smooth muscle, including vasodilatation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscle. Loratadine does not cross the blood-brain barrier and does not cause central nervous system effects.NCI ThesaurusU.S. National Cancer Institute, 2021
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A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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