Cell Function
macrophage activation
mac·ro·phage ac·tiva·tion
Subclass of:
Immunologic Cytotoxicity
Definitions related to macrophage activation:
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A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.Gene Ontology DictionaryGene Ontology Consortium, 2021
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The process of altering the morphology and functional activity of macrophages so that they become avidly phagocytic. It is initiated by lymphokines, such as the macrophage activation factor (MAF) and the macrophage migration-inhibitory factor (MMIF), immune complexes, C3b, and various peptides, polysaccharides, and immunologic adjuvants.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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