Hormone
medroxyprogesterone
[ mi-drok-see-proh-jes-tuh-rohn ]
Brand Names:
Depo-Provera; depo-subQ provera; Provera
Effect:
Decreased Follicle Stimulating Hormone Secretion; Decreased Growth Hormone Secretion; Gonadotropin Releasing Hormone Alteration; Inhibit Ovarian Follicular Phase; Inhibit Ovulation; Stimulate Breast Glandular Development
May Prevent:
Pregnancy
May Treat:
Amenorrhea;
Breast Neoplasms;
Carcinoma, Renal Cell;
Endometrial Hyperplasia;
Endometrial Neoplasms;
Hypoventilation;
Uterine Hemorrhage
More Information:
Definitions related to medroxyprogesterone:
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A hormonal anticancer drug that is also used in cancer prevention. It belongs to the family of drugs called progestins.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A synthetic derivative of progesterone administered as an acetate salt (medroxyprogesterone acetate) with antiestrogenic activity. As a do all progestins, medroxyprogesterone binds to and activates nuclear receptors which subsequently bind to and activate target genes for transcription. As an antiestrogen, this agent may inhibit the growth-stimulating effects of estrogen on estrogen-sensitive tumor cells. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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A synthetic progestational hormone used in veterinary practice as an estrus regulator.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Synthetic progestin derived from 17-hydroxyprogesterone; a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been used to treat breast and endometrial neoplasms.CRISP ThesaurusNational Institutes of Health, 2006
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Depo-Provera is a well-known brand name for medroxyprogesterone acetate, a contraceptive injection that contains the hormone progestin. Depo-Provera is given as an injection every three months. Depo-Provera typically suppresses ovulation, keeping your ovaries from releasing an egg. It also thickens cervical mucus to keep sperm from...Mayo Foundation for Medical Education and Research
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