Pharmacologic Substance
mefenamic acid
Effect:
Decreased Platelet Activating Factor Production; Decreased Prostaglandin Production; Decreased Thromboxane Production
May Prevent:
Pain
May Treat:
Dysmenorrhea;
Fever;
Menorrhagia;
Premenstrual Syndrome
More Information:
Definitions related to mefenamic acid:
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A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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An anthranilic acid and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Mefenamic acid inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of mefenamic acid. Mefenamic acid also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.NCI ThesaurusU.S. National Cancer Institute, 2021
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