Cell Function
meiotic recombination
Definitions related to meiotic recombination:
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Any type of homology-dependent DNA strand exchange occurring during gametogenesis and involving synapsis of parental homologs, strand breakage and exchange of segments to yield unique combinations of genes in the gamete. Disruptions in this process may result in aneuploidy of the resulting gametes, infertility in affected patients and trisomy in progeny.NCI ThesaurusU.S. National Cancer Institute, 2021
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(reciprocal meiotic recombination) The cell cycle process in which double strand breaks are formed and repaired through a single or double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.Gene Ontology DictionaryGene Ontology Consortium, 2021
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