Pharmacologic Substance
mesalamine
Brand Names:
Apriso; Asacol; Canasa; Delzicol; Lialda; Pentasa; Rowasa; Zaldyon
Effect:
Decreased Leukotriene Activity; Decreased Platelet Aggregation; Decreased Prostaglandin Production; Decreased Thromboxane Production
May Treat:
Colitis, Ulcerative; Proctitis; Sigmoid Diseases
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to mesalamine:
  • An agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through inhibition of cyclooxygenase and prostaglandin production. Following rectal or oral administration, only a small amount of mesalamine is absorbed; the remainder, acting topically, reduces bowel inflammation, diarrhea, rectal bleeding and stomach pain. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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