Pharmacologic Substance
mesalamine
Brand Names:
Apriso; Asacol; Canasa; Delzicol; Lialda; Pentasa; Rowasa; Zaldyon
Effect:
Decreased Leukotriene Activity; Decreased Platelet Aggregation; Decreased Prostaglandin Production; Decreased Thromboxane Production
May Treat:
Colitis, Ulcerative;
Proctitis;
Sigmoid Diseases
More Information:
Definitions related to mesalamine:
-
An agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through inhibition of cyclooxygenase and prostaglandin production. Following rectal or oral administration, only a small amount of mesalamine is absorbed; the remainder, acting topically, reduces bowel inflammation, diarrhea, rectal bleeding and stomach pain. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
-
An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
Return to OpenMD Medical Dictionary
> M
This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.