Disease or Syndrome
microscopic polyangiitis
Subclass of:
Cerebral Small Vessel Diseases
Definitions related to microscopic polyarteritis:
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(microscopic polyangiitis) A primary systemic vasculitis of small- and some medium-sized vessels. It is characterized by a tropism for kidneys and lungs, positive association with anti-neutrophil cytoplasmic antibodies (ANCA), and a paucity of immunoglobulin deposits in vessel walls.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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(microscopic polyangiitis) Microscopic polyangiitis (MPA) is an inflammatory, necrotizing, systemic vasculitis that affects predominantly small vessels (i.e. small arteries, arterioles, capillaries, venules) in multiple organs.OrphaNetINSERM, 2021
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(microscopic polyangiitis) Systemic vasculitis affecting small vessels that is necrotizing and non-granulomatous, with little to no immune complex deposition. Clinically it is characterized by involvement of the kidneys, skin, lung, and peripheral nerves. Antineutrophil cytoplasmic antibody (anti-myeloperoxidase (anti-MPO)) is positive in most cases.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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A systemic necrotizing vasculitis that typically affects the small and medium-sized muscular arteries. In some cases, however, microscopic vessels are also affected (e.g., in the kidneys), a condition that has been called microscopic polyarteritis or polyangiitis; this disorder is felt to be more closely associated with Wegener granulomatosis than to classic polyarteritis nodosa.NCI ThesaurusU.S. National Cancer Institute, 2021
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Microscopic polyangiitis is a systemic necrotizing vasculitis without immune globulin deposition (pauci-immune) that affects mainly small vessels. It may begin as a pulmonary-renal syndrome with rapidly progressing glomerulonephritis and alveolar hemorrhage, but the pattern of disease depends on the organs affected. Diagnosis is made by...Merck & Co., Inc., 2020
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Microscopic polyangiitis (MPA) is vasculitis of small vessels. It was initially considered as a microscopic form of polyarteritis nodosa (PAN).WebMD, 2019
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Microscopic polyangiitis (MPA) is a disorder that causes blood vessel inflammation (vasculitis), which can lead to organ damage. The kidneys, lungs, nerves, skin, and joints are the most commonly affected areas of the body. MPA is diagnosed in people of all ages, all ethnicities, and both genders. The cause of this disorder is unknown.National Center for Advancing Translational Sciences
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