Pharmacologic Substance
mometasone furoate Audio
[ moh-meh-tuh-sone fyoor-oh-ayt ]
Effect:
Decreased Leukotriene Activity; Decreased Prostaglandin Activity; Decreased Protein Synthesis; Decreased Thromboxane Activity; Vasoconstriction
May Treat:
Facial Dermatoses; Foot Dermatoses; Hand Dermatoses; Inflammation; Leg Dermatoses; Pruritus; Rhinitis, Allergic, Perennial; Scalp Dermatoses
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to mometasone furoate:
  • A drug that is used in a cream to treat certain skin conditions and in a nasal spray to treat sinus problems caused by allergies. It is being studied as a way to treat inflammation of the skin caused by radiation therapy. Elocon is a type of corticosteroid.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A pregnadienediol derivative ANTI-ALLERGIC AGENT and ANTI-INFLAMMATORY AGENT that is used in the management of ASTHMA and ALLERGIC RHINITIS. It is also used as a topical treatment for skin disorders.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • The furoate ester form of mometasone, a synthetic topical glucocorticoid receptor (GR) agonist with anti-inflammatory, anti-pruritic and vasoconstrictive properties. Upon administration, mometasone binds to cytoplasmic GRs and subsequently activates GR-mediated gene expression. This results in the synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators. Specifically, mometasone appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from phospholipid membrane by phospholipase A2.
    NCI
    U.S. National Cancer Institute, 2021
Try this search on: Farlex, Merriam-Webster, Oxford Dictionary, or Wordnik

This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.