Pharmacologic Substance
fluorometholone
Brand Names:
Flarex; FML; FML Forte Liquifilm; FML-S
Effect:
Decreased Glucocorticoid Secretion; Decreased Leukotriene Activity; Decreased Prostaglandin Activity; Decreased Thromboxane Activity
May Treat:
Conjunctivitis;
Inflammation;
Keratitis
More Information:
Definitions related to fluorometholone:
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A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Fluorometholone exerts its effects by interacting with cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.NCI ThesaurusU.S. National Cancer Institute, 2021
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