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motexafin gadolinium
[ moh-tek-suh-fin ga-doh-lih-nee-um ]
Definitions related to motexafin gadolinium:
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A substance that is being studied in the treatment of cancer. It may make tumor cells more sensitive to radiation therapy, improve tumor images using magnetic resonance imaging (MRI), and kill cancer cells. It is a type of metalloporphyrin complex.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A synthetic metallotexaphyrin with radiosensitizing and chemosensitizing properties. Motexafin gadolinium accumulates in tumor cells preferentially due to their increased rates of metabolism, generating reactive oxygen species (ROS) intracellularly and lowering the tumor cell apoptotic threshold to ionizing radiation and chemotherapy. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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