Antibiotic
mupirocin
Brand Names:
Bactroban; Centany; Muricin; Pirnuo
Effect:
Decreased RNA Replication; Decreased Transcription to RNA; Increased Protein Synthesis
May Treat:
Impetigo
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to mupirocin:
  • A natural crotonic acid derivative extracted from Pseudomonas fluorescens. Mupirocin inhibits bacterial protein synthesis by specific reversible binding to bacterial isoleucyl tRNA synthase. With excellent activity against gram-positive staphylococci and streptococci, it is primarily used for treatment of primary and secondary skin disorders, nasal infections, and wound healing. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • A topically used antibiotic from a strain of Pseudomonas fluorescens. It has shown excellent activity against gram-positive staphylococci and streptococci. The antibiotic is used primarily for the treatment of primary and secondary skin disorders, nasal infections, and wound healing.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Mupirocin inhibits bacterial RNA and protein synthesis. It is available only as a 2% topical preparation, which is bactericidal against staphylococci and beta-hemolytic streptococci. Systemic absorption of topical mupirocin is negligible.
    Merck Manuals
    Merck & Co., Inc., 2025
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.