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Related terms:
fibroma
fibrosarcoma
histiocytoma
Neoplastic Process
myofibromatosis
Subclass of:
Neoplasms, Fibrous Tissue
Definitions related to myofibromatosis:
  • A benign, multifocal, nodular and well-circumscribed neoplasm usually seen as a congenital neoplasm or in the first year of life. It is characterized by a biphasic growth pattern and is composed of small, undifferentiated mesenchymal cells associated with branching thin-walled vessels and more mature neoplastic spindle cells with abundant eosinophilic cytoplasm in a collagenous stroma.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A condition characterized by multiple formations of myofibromas (LEIOMYOMA).
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A mesenchymal neoplasm characterized by solitary or multiple nodules involving the skin, striated muscles, bones and, sometimes, viscera. It usually appears as a subcutaneous nodule, but can also appear as an ulcer, pedunculated lesion, or similar to a hemangioma. Histology shows well-circumscribed tapered cell lobes, resembling smooth muscle cells. At its center, perivascular round cells (hemangiopericitoides) are usually observed, giving a biphasic appearance.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.

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