• Death of a group of cells in an organ or tissue. (INHAND)
  CDISC Terminology
  Clinical Data Interchange Standards Consortium (CDISC), 2021
• Refers to the death of tissues.
  NCI Dictionary of Cancer Terms
  U.S. National Cancer Institute, 2021
• (necrotic) Relating to or affected by necrosis.
  NCI
  U.S. National Cancer Institute, 2021
• Sum of the morphological changes indicative of cell death and caused by the progressive degradation action of enzymes; may affect groups of cells or part of a structure or an organ.
  CRISP Thesaurus
  National Institutes of Health, 2006
• The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2025
• The pathologic death of cells or of a portion of tissue or organ resulting from irreversible damage.
  U.S. FDA Glossary
  U.S. Food & Drug Administration, 2021
• The premature death of living cells or tissues.
  Harvard Dictionary of Health Terms
  Harvard Medical Publishing, 2011
• (necrotic process) A cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.
  NCI
  U.S. National Cancer Institute, 2021
• Necrosis, death of a circumscribed area of plant or animal tissue as a result of disease or injury. Necrosis is a form of premature tissue death, as opposed to the spontaneous natural death or wearing out of tissue, which is known as necrobiosis. Necrosis is further distinguished from apoptosis, or...
  Encyclopedia Britannica
  Encyclopedia Britannica, Inc., 2025