Pathologic Function
ototoxicity
Subclass of:
Adverse reaction to drug; Pathologic Processes; Radiation injury; Ear Diseases
Definitions related to ototoxicity:
  • Damage to the EAR or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Damage to the inner ear as a result of exposure to drugs or chemicals.
    NCI
    U.S. National Cancer Institute, 2021
  • Any drug with the potential to cause toxic reactions to structures of the inner ear, including the cochlea, vestibule, semicircular canals, and otoliths, is considered ototoxic. Drug-induced damage to these structures of the auditory and balance system can result in hearing loss, tinnitus, and dysequilibrium or dizziness.
    Medscape
    WebMD, 2025
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.