Pharmacologic Substance
pancuronium
Effect:
Decreased Striated Muscle Contraction
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to pancuronium:
  • A bis-quaternary steroid that is a competitive nicotinic antagonist. As a neuromuscular blocking agent it is more potent than CURARE but has less effect on the circulatory system and on histamine release.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A synthetic, long-acting bis-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscle relaxant activity. Pancuronium competitively binds to and blocks the nicotinic acetylcholine receptor at the neuromuscular junction, thereby preventing acetylcholine (ACh) binding and resulting in skeletal muscle relaxation and paralysis.
    NCI
    U.S. National Cancer Institute, 2021
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