Disease or Syndrome
paraproteinemia
Subclass of:
Immunoproliferative Disorders; Blood Protein Disorders
Definitions related to paraproteinemias:
  • A plasma cell disorder in which an abnormal amount of a single immunoglobulin is present in the serum. Paraproteinemias may be seen in conjunction with various carcinomas, chronic inflammatory and infectious conditions, and other diseases. --2004
    NCI
    U.S. National Cancer Institute, 2021
  • An abnormal immunoglobulin or part of an Ig (light chain) in the circulation. Paraproteins are typically produced by a clonal population of B-cell derived plasma cells.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
  • A group of related diseases characterized by an unbalanced or disproportionate proliferation of immunoglobulin-producing cells, usually from a single clone. These cells frequently secrete a structurally homogeneous immunoglobulin (M-component) and/or an abnormal immunoglobulin.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
Try this search on: Farlex, Merriam-Webster, Oxford Dictionary, or Wordnik

This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.