Disease or Syndrome
agammaglobulinemia Audio
a·gam·ma·glob·u·li·ne·mi·a [ ey-gam-uh-glob-yuh-luh-nee-mee-uh ]
Subclass of:
Immunologic Deficiency Syndromes; Lymphoproliferative Disorders; Blood Protein Disorders
Definitions related to agammaglobulinemia:
  • A lasting absence of total IgG and total IgA and total IgM in the blood circulation, whereby at most trace quantities can be measured.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2021
  • An immunologic deficiency state characterized by an extremely low level of generally all classes of gamma-globulin in the blood.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • Agammaglobulinemia, or hypogammaglobulinemia, is the most common of the primary immunodeficiencies, accounting for approximately 50% of cases. Three major types can be described: X-linked, early onset, and late onset.
    Medscape
    WebMD, 2019
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