(parkinsonism) Characteristic neurologic anomaly resulting from degeneration of dopamine-generating cells in the substantia nigra, a region of the midbrain, characterized clinically by shaking, rigidity, slowness of movement and difficulty with walking and gait.

(parkinsonism) One or more of the following symptoms including bradykinesia associated with rigidity, resting tremor, gait disturbance, which may be due to multiple etiologies.

A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.

Parkinsonism refers to symptoms of Parkinson disease (such as slow movements and tremors) that are caused by another condition. Parkinsonism is caused by brain disorders, brain injuries, or certain drugs and toxins.

Parkinsonism, a group of chronic neurological disorders characterized by progressive loss of motor function resulting from the degeneration of neurons in the area of the brain that controls voluntary movement. Parkinsonism was first described in 1817 by the British physician James Parkinson in his...