Biologically Active Substance
paxillin
Subclass of:
Adaptor Proteins, Signal Transducing; LIM Domain Proteins; Phosphoproteins
Definitions related to paxillin:
  • Focal adhesion protein that is part of the beta2 integrin dependent signal transduction pathways; active during embryonic development.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Paxillin is a signal transducing adaptor protein that localizes to FOCAL ADHESIONS via its four LIM domains. It undergoes PHOSPHORYLATION in response to integrin-mediated CELL ADHESION, and interacts with a variety of proteins including VINCULIN; FOCAL ADHESION KINASE; PROTO-ONCOGENE PROTEIN PP60(C-SRC); and PROTO-ONCOGENE PROTEIN C-CRK.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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