Pharmacologic Substance
peptichemio
Subclass of:
Oligopeptides; Melphalan
Definitions related to peptichemio:
  • A mixture of six synthetic oligopeptides in which the peptides are conjugated to metamelphalan, with alkylating and potential antineoplastic activity. Peptichemio causes crosslinking of DNA, thereby preventing DNA replication and eventually cellular proliferation.
    NCI
    U.S. National Cancer Institute, 2021
  • A mixture of six synthetic oligopeptides, each containing MELPHALAN. It is used as a broad-spectrum antineoplastic due to its alkylating and antimetabolic actions but, is toxic to bone marrow, gastrointestinal system and vasculature.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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