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Disease or Syndrome
peripheral neuropathy Audio
pe·riph·er·al neu·rop·a·thy [ puh-rif-er-uhl noo-rop-uh-thee, nyoo- ]
Also called:
Neuritis; Peripheral neuritis
Definitions related to peripheral neuropathy:
  • A disorder affecting one or more peripheral nerves. It is manifested with pain, tingling, numbness, and/ or muscle weakness. Causes may include physical injury, toxic substances, viral infection and systemic illness.
    NICHD Pediatric Terminology
    U.S. National Cancer Institute, 2021
  • A disorder affecting the peripheral nervous system. It manifests with pain, tingling, numbness, and muscle weakness. It may be the result of physical injury, toxic substances, viral diseases, diabetes, renal failure, cancer, and drugs.
    NCI
    U.S. National Cancer Institute, 2021
  • A nerve problem that causes pain, numbness, tingling, swelling, or muscle weakness in different parts of the body. It usually begins in the hands or feet and gets worse over time. Neuropathy may be caused by physical injury, infection, toxic substances, disease (such as cancer, diabetes, kidney failure, or malnutrition), or drugs, including anticancer drugs.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • Damage to the long nerves radiating from the spine to the arms and legs.
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
  • Peripheral neuropathy is a general term for any disorder of the peripheral nervous system. The main clinical features used to classify peripheral neuropathy are distribution, type (mainly demyelinating versus mainly axonal), duration, and course.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
  • Peripheral neuropathy is dysfunction of one or more peripheral nerves (the part of a nerve distal to the root and plexus). It includes numerous syndromes characterized by varying degrees of sensory disturbances, pain, muscle weakness and atrophy, diminished deep tendon reflexes, and vasomotor symptoms, alone or in any combination....
    Merck Manuals
    Merck & Co., Inc., 2025
  • Peripheral neuropathy, a result of damage to the nerves outside of the brain and spinal cord (peripheral nerves), often causes weakness, numbness and pain, usually in your hands and feet. It can also affect other areas of your body.
    Mayo Clinic
    Mayo Foundation for Medical Education and Research, 2025
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.

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