Pharmacologic Substance
phenothiazine
phe·no·thi·a·zine [ fee-nuh-thahy-uh-zeen, -zin ]
Definitions related to phenothiazine:
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3-ring structure of two benzene rings joined by a sulfur and a nitrogen atom; an important class of antipsychotic and other drugs which act by disrupting monoamine transmitter systems.CRISP ThesaurusNational Institutes of Health, 2006
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A class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain, potentially preventing chemotherapy-induced emesis. In addition, these agents have peripherally or centrally antagonistic activity against alpha adrenergic, serotonergic, histaminic, and muscarinic receptors.NCI ThesaurusU.S. National Cancer Institute, 2021
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A type of drug that is used to treat severe mental and emotional disorders, severe nausea and vomiting, and certain other conditions. It belongs to the families of drugs called antipsychotics and antiemetics.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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Phenothiazine, widely used anthelmintic (worming agent) in veterinary medicine. Phenothiazine is an organic compound effective against a broad range of parasites in cattle, horses, poultry, sheep, and swine. A highly toxic drug, it is not recommended for human use and is not effective in dogs or...Encyclopedia Britannica, Inc., 2020
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