Neoplastic Process
pilocytic astrocytoma
Definitions related to pilocytic astrocytoma:
  • A WHO grade 1, relatively circumscribed, slowly growing, often cystic astrocytoma occurring in children and young adults. Histologically it is characterized by a biphasic pattern with compacted bipolar cells associated with Rosenthal fibers and multipolar cells associated with microcysts and eosinophilic bodies/hyaline droplets. (WHO)
    NCI
    U.S. National Cancer Institute, 2021
  • The most common form of astrocytoma (WHO Grade I) in childhood. These typically have MAPK signaling pathway abnormalities.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
  • Pilocytic astrocytoma is an often benign, slow-growing tumor of the brain or spinal cord. The tumor may be in the form of a cyst and usually does not spread to nearby tissues. Symptoms vary depending upon the size and location of the tumor. Most symptoms result from increased pressure on the brain and include headaches, nausea, vomiting,...
    NIH Genetic and Rare Diseases
    National Center for Advancing Translational Sciences
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