Pharmacologic Substance
pixantrone
[ pik-san-trone ]
Definitions related to pixantrone:
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A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called antitumor antibiotics.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity.NCI ThesaurusU.S. National Cancer Institute, 2021
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