Neoplastic Process
polycythemia vera
[ pah-lee-sy-thee-mee-uh vayr-uh ]
Subclass of:
Myeloproliferative disease;
Bone Marrow Neoplasms
Also called:
Primary Polycythemia
Definitions related to polycythemia vera:
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A chronic myeloproliferative neoplasm characterized by an increased red blood cell production. The bone marrow is hypercellular due to a panmyelotic proliferation typically characterized by pleomorphic megakaryocytes. The major symptoms are related to hypertension, splenomegaly or to episodes of thrombosis and/or hemorrhage.NCI ThesaurusU.S. National Cancer Institute, 2021
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A disease in which there are too many red blood cells in the bone marrow and blood, causing the blood to thicken. The number of white blood cells and platelets may also increase. The extra blood cells may collect in the spleen and cause it to become enlarged. They may also cause bleeding problems and make clots form in blood vessels.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Myeloproliferative disorder characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume; associated frequently with splenomegaly, leukocytosis, and thrombocythemia.CRISP ThesaurusNational Institutes of Health, 2006
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Polycythemia vera (PV) is a chronic myeloproliferative neoplasm characterized by an increase in morphologically normal red cells (its hallmark), but also white cells and platelets. Ten to 30% of patients eventually develop myelofibrosis and marrow failure; acute leukemia occurs spontaneously in 1.0 to 2.5%. There is an increased risk of...Merck & Co., Inc., 2020
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Polycythemia vera (PV) is a stem cell disorder characterized as a panhyperplastic, malignant, and neoplastic marrow disorder. Its most prominent feature is an elevated absolute red blood cell mass because of uncontrolled red blood cell production.WebMD, 2019
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Polycythemia vera (pol-e-sy-THEE-me-uh VEER-uh) is a type of blood cancer. It causes your bone marrow to make too many red blood cells. These excess cells thicken your blood, slowing its flow, which may cause serious problems, such as blood clots.Mayo Foundation for Medical Education and Research
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Polycythemia vera is a condition characterized by an increased number of red blood cells in the bloodstream (erythrocytosis). Affected people may also have excess white blood cells and platelets. Conditions where the body makes too many of these cells are known as myeloproliferative neoplasms. These extra cells cause the blood to be...National Center for Advancing Translational Sciences
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Polycythemia vera (PV) belongs to the group of Philadelphia chromosome-negative myeloproliferative neoplasms. It is a clonal hematopoietic disorder characterized clinically by erythrocytosis and often thrombocytosis, leukocytosis, and splenomegaly. It is associated with an increased risk of thrombosis and hemorrhage. It may progress to...Athenahealth, Inc., 2019
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