Receptor
presenilin
Subclass of:
Membrane Proteins
Definitions related to presenilins:
  • Membrane protein associated with early onset familial Alzheimer's disease.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Integral membrane proteins and essential components of the gamma-secretase complex that catalyzes the cleavage of membrane proteins such as NOTCH RECEPTORS and AMYLOID BETA-PEPTIDES precursors. Mutations of presenilins lead to presenile ALZHEIMER DISEASE with onset before age 65 years.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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