Pharmacologic Substance
progesterone antagonist
pro·ges·ter·one an·tag·o·nist
Definitions related to progesterone antagonist:
  • (antiprogestin) A substance that prevents cells from making or using progesterone (a hormone that plays a role in the menstrual cycle and pregnancy). Antiprogestins may stop some cancer cells from growing and they are being studied in the treatment of breast cancer. An antiprogestin is a type of hormone antagonist.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A substance that blocks the activity of a progestin.
    NCI
    U.S. National Cancer Institute, 2021
  • Antiprogestin, any substance that blocks the synthesis or action of the hormone progesterone. Antiprogestins are used for contraception, labour induction, and treatment of endometriosis and breast cancer. Mifepristone was the first antiprogestin to be described and was marketed under various trade...
    Encyclopedia Britannica
    Encyclopedia Britannica, Inc., 2025
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