Biologically Active Substance
protein C
pro·tein c
Brand Names:
Ceprotin; Kcentra
Definitions related to protein c:
  • A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • The normal protein C level in a healthy adult is approximately 65-135 IU/dL. For a healthy term infant, the average value is 40 IU/dL, which will increase as the child ages, to approximately 60 IU/dL; the adult range typically is not reached until after puberty.
    Medscape
    WebMD, 2025
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