Vitamin
pyridoxal phosphate
pyr·i·dox·al phos·phate
Effect:
Cellular Activity Alteration
May Prevent:
Drug-Related Side Effects and Adverse Reactions; Vitamin B 6 Deficiency
May Treat:
Drug-Related Side Effects and Adverse Reactions;
Seizures;
Vitamin B 6 Deficiency
More Information:
Definitions related to pyridoxal phosphate:
-
The active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and deamination reactions; it is necessary for the synthesis of amino acids and amino acid metabolites, and for the synthesis and/or catabolism of certain neurotransmitters, including the conversion of glutamate into gamma-aminobutyric acid (GABA) and levodopa into dopamine. PLP can be used as a dietary supplement in cases of vitamin B6 deficiency. Reduced levels of PLP in the brain can cause neurological dysfunction.NCI ThesaurusU.S. National Cancer Institute, 2021
-
This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
Return to OpenMD Medical Dictionary
> P
This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.