• A rare inherited retinal dystrophy disorder characterized by spots of black bone-spicule pigmentation of the retinal pigment epithelium. It is manifested with decreased vision in low light or in the night, followed by decreased peripheral vision, and, eventual decreased central vision. It may lead to blindness.
  NCI Thesaurus
  U.S. National Cancer Institute, 2021
• Group of inherited abnormalities in the retina; characterized by night blindness, retinal atrophy, weakening of the retinal vessels, pigment clumping, and contraction of the visual field.
  CRISP Thesaurus
  National Institutes of Health, 2006
• Hereditary, progressive degeneration of the retina due to death of ROD PHOTORECEPTORS initially and subsequent death of CONE PHOTORECEPTORS. It is characterized by deposition of pigment in the retina.
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2021
• Retinitis pigmentosa is a slowly progressive, bilateral degeneration of the retina and retinal pigment epithelium caused by various genetic mutations. Symptoms include night blindness and loss of peripheral vision. Diagnosis is by funduscopy, which shows pigmentation in a bone-spicule configuration in the equatorial retina, narrowing of...
  Merck Manuals
  Merck & Co., Inc., 2020
• Retinitis pigmentosa (RP) is a group of inherited disorders characterized by progressive peripheral vision loss and night vision difficulties (nyctalopia) that can lead to central vision loss.With advances in molecular research, it is now known that RP constitutes many retinal dystrophies and retinal pigment epithelium (RPE) dystro...
  Medscape
  WebMD, 2019
• Retinitis pigmentosa (RP) is a group of inherited eye diseases that affect the light-sensitive part of the eye (retina). RP causes cells in the retina to die, causing progressive vision loss. The first sign of RP usually is night blindness. As the condition progresses, affected individuals develop tunnel vision (loss of peripheral...
  NIH Genetic and Rare Diseases
  National Center for Advancing Translational Sciences
• Retinitis pigmentosa (RP) is a term that encompasses a broad category of hereditary conditions of retinal degeneration that share a common pathophysiology. Symmetrical retinal degeneration is caused by a genetic mutation in 1 of over 100 different genes, leading to loss of rod and cone photoreceptors in the retina. Inheritance can be...
  Epocrates
  Athenahealth, Inc., 2019
• Retinitis pigmentosa, group of hereditary eye diseases in which progressive degeneration of the retina leads to severe impairment of vision. In the usual course of disease, the light-sensitive structures called rods--which are the visual receptors used in dim light--are destroyed early on, causing...
  Encyclopedia Britannica
  Encyclopedia Britannica, Inc., 2020