Pharmacologic Substance
retinoid
ret·i·noid [ ret-n-oid ]
Subclass of:
Carotenoids
Definitions related to retinoids:
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A nutrient that the body needs in small amounts to function and stay healthy. Retinoic acid is made in the body from vitamin A and helps cells to grow and develop, especially in the embryo. A form of retinoic acid made in the laboratory is put on the skin to treat conditions such as acne and is taken by mouth to treat acute promyelocytic leukemia (a fast-growing cancer in which there are too many immature blood-forming cells in the blood and bone marrow). Retinoic acid is being studied in the prevention and treatment of other types of cancer.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A synthetic, vitamin A-like compound.Harvard Dictionary of Health TermsHarvard Medical Publishing, 2011
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Class of compounds consisting of four isoprenoid units joined in a head-to-tail manner and customarily containing five conjugated double bonds.CRCH Nutrition TerminologyCancer Research Center of Hawaii, University of Hawaii, 2021
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Retinol and its derivatives; C(20) polyunsaturated, cyclic, lipid soluble alcohol; deficiency results in night blindness and certain epithelial disorders.CRISP ThesaurusNational Institutes of Health, 2006
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A group of tetraterpenes, with four terpene units joined head-to-tail. Biologically active members of this class are used clinically in the treatment of severe cystic ACNE; PSORIASIS; and other disorders of keratinization.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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(retinoic acid agent) A group of agents that includes retinol (Vitamin A) and related compounds with potential antineoplastic and/or chemopreventive activities. A retinoic acid agent binds to and/or activates specific nuclear retinoic acid receptors (RARs) and retinoid X receptors (RXRs), thereby modulating transcription of genes responsible for cell differentiation and proliferation. A retinoic acid agent may exhibit immunomodulatory and anti-inflammatory properties and may inhibit ornithine decarboxylase, resulting in a decrease in polyamine synthesis and keratinization. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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